SARS-CoV-2 neutralizing antibody development strategies

SARS-CoV-2 neutralizing antibody development strategies

In December 2019 a novel coronavirus was detected in Wuhan Metropolis of Hubei Province-China. Owing to a excessive charge of transmission from human to human, the brand new virus known as SARS-CoV-2 differed from others by its unexpectedly fast unfold. The World Well being Group (WHO) described the latest coronavirus epidemic as a world pandemic in March 2020. The virus unfold triggered a well being disaster (the COVID-19 illness) inside three months, with socioeconomic implications.

Mouse Monoclonal Antibody

28298-100Tests 100 Tests
EUR 499

Mouse Monoclonal Antibody

28298-25Tests 25 Tests
EUR 245

PCNA Mouse Monoclonal Antibody

21801-100ul 100ul
EUR 252

PCNA Mouse Monoclonal Antibody

21801-50ul 50ul
EUR 187

PCNA Mouse Monoclonal Antibody

37978-100ul 100ul
EUR 252

PCNA Mouse Monoclonal Antibody

37978-50ul 50ul
EUR 187

EGFR Mouse Monoclonal Antibody

37996-100ul 100ul
EUR 252

EGFR Mouse Monoclonal Antibody

37996-50ul 50ul
EUR 187

CD20 Mouse Monoclonal Antibody

38003-100ul 100ul
EUR 252

CD20 Mouse Monoclonal Antibody

38003-50ul 50ul
EUR 187

CD23 Mouse Monoclonal Antibody

38004-100ul 100ul
EUR 252

CD23 Mouse Monoclonal Antibody

38004-50ul 50ul
EUR 187

CD68 Mouse Monoclonal Antibody

38005-100ul 100ul
EUR 252

CD68 Mouse Monoclonal Antibody

38005-50ul 50ul
EUR 187

CK19 Mouse Monoclonal Antibody

38006-100ul 100ul
EUR 252

CK19 Mouse Monoclonal Antibody

38006-50ul 50ul
EUR 187

p53 Mouse Monoclonal Antibody

38007-100ul 100ul
EUR 252

p53 Mouse Monoclonal Antibody

38007-50ul 50ul
EUR 187

CK7 Mouse Monoclonal Antibody

38009-100ul 100ul
EUR 252

CK7 Mouse Monoclonal Antibody

38009-50ul 50ul
EUR 187
No authorised targeted-therapies can be found for COVID-19, but. Nonetheless, it’s foreseen that antibody-based remedies could present a direct remedy for sufferers. Present neutralizing antibody improvement research primarily goal the S protein among the many structural parts of SARS-CoV-2, which mediates the cell entry of the virus via the angiotensin changing enzyme 2 (ACE2) receptor of host cells.
gentaurprices
Gentaurprices
This evaluate goals to supply a number of the neutralizing antibody improvement methods for SARS-CoV-2 and in vitro and in vivo neutralization assays.
Key phrases: COVID-19; SARS-CoV-2; animal fashions; show applied sciences; human monoclonal antibody; human scFv; neutralizing antibodies; neutralizing assays.

Antibody Responses after Classroom Publicity to Instructor with Coronavirus Illness, March 2020

After getting back from Europe to the USA, on March 1, 2020, a symptomatic trainer obtained constructive check outcomes for extreme acute respiratory syndrome coronavirus 2. Of the 21 college students uncovered to the trainer within the classroom, serologic outcomes recommended previous an infection for two.Classroom contact could end in virus transmission.
Key phrases: 2019 novel coronavirus illness; COVID-19; SARS-CoV-2; United States; adolescents; classroom; coronavirus illness; respiratory infections; extreme acute respiratory syndrome coronavirus 2; trainer; viruses; zoonoses.

Virus particular antibody – primarily based cures for the pressing prevention and remedy of Ebola virus illness

The Ebola virus (member of Ebolavirus genus Filoviridae household) is the etiologic agent of extraordinarily hazard human illness with excessive mortality charges (as much as 90%). A very powerful parts of spectrum of therapeutics for particular prophylactic and present of illness, attributable to Ebola virus, are prepares, primarily based on virus particular antibodies (convalescent’s plasma, geterologic immunoglobulins, monoclonal antibodies.
The usage of completely different class therapeutics, primarily based on virus particular antibodies, the potential enhancements of its composition and technique of its utility for particular prophylactic and present of illness, attributable to Ebola virus, are thought-about on this evaluate.
Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280
anti- immunoglobulin kappa antibody
FNab04295 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:20-1:200
  • Immunogen: immunoglobulin kappa locus
  • Gene ID: 50802
  • Research Area: Immunology
Description: Antibody raised against immunoglobulin kappa
Anti-immunoglobulin kappa antibody
PAab04295 100 ug
EUR 386
Anti-hRPP20 Immunoglobulin antibody
STJ16100943 100 µg
EUR 892
Anti-hRRP4 Immunoglobulin antibody
STJ16100944 100 µg
EUR 892
Anti-Human Immunoglobulin IgA antibody
STJ16100584 1 mL
EUR 530
Anti-Human Immunoglobulin IgE antibody
STJ16100585 1 mL
EUR 530
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100950 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100951 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100952 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100954 100 µg
EUR 1310
Anti-Polymeric immunoglobulin receptor/PIGR Antibody
A01624 100ug/vial
EUR 294
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
abx052587-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
20-abx150684
  • EUR 7504.00
  • EUR 3996.00
  • EUR 926.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-10x96wellstestplate 10x96-wells test plate
EUR 5386
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-1x48wellstestplate 1x48-wells test plate
EUR 531.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-1x96wellstestplate 1x96-wells test plate
EUR 716
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-5x96wellstestplate 5x96-wells test plate
EUR 2922
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
4-AEA546Hu
  • EUR 5437.00
  • EUR 2873.00
  • EUR 717.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Immunoglobulin A elisa. Alternative names of the recognized antigen: n/a
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) CLIA Kit
20-abx490647
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 20 working days.
Human Anti-Immunoglobulin A Antibody ELISA Kit (Anti-IgA)
RK00894 96 Tests
EUR 521
immunoglobulin Kappa (immunoglobulin kappa) Antibody
abx234295-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.
Mouse Anti Rat Immunoglobulin A Monoclonal Antibody
DMABT-49896MR 0.5 mg
EUR 892
Human Anti-Immunoglobulin Binding Protein antibody(BIP)
QY-E05388 96T
EUR 361
Anti-Chicken IgG Heavy Chain Immunoglobulin antibody
STJ16100953 100 µg
EUR 474
ELISA kit for Human Anti-IgA (Anti-Immunoglobulin A Antibody)
ELK8046 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antigen. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated secondary antibody. After TMB substrate soluti
  • Show more
Description: A competitive Inhibition ELISA kit for detection of Anti-Immunoglobulin A Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Anti-Immunoglobulin A Antibody ELISA Kit (Human) (OKCD01288)
OKCD01288 96 Wells
EUR 936
Description: Description of target: Anti-Immunoglobulin A antibody;Species reactivity: Human;Application: ;Assay info: Assay Method: Quantitative Reverse Capture Sandwich ELISA;Sensitivity: 2.59 ng/mL
Human Anti-Tuberculous Glycolipid Immunoglobulin G(anti-TBGL-IgG)ELISA kit
QY-E05511 96T
EUR 361
Mouse anti-Rabbit Immunoglobulin Light Chain (IGL) Antibody (HRP)
abx401391-05ml 0.5 ml
EUR 495
  • Shipped within 1 week.
Immunoglobulin (IG) Antibody
abx024071-200ug 200 ug
EUR 843
  • Shipped within 5-10 working days.
Yolk Immunoglobulin Antibody
abx110397-500ug 500 ug
EUR 300
  • Shipped within 5-10 working days.
Immunoglobulin J Protein
20-abx261047
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.
Yolk Immunoglobulin Polyclonal Antibody
42094-100ul 100ul
EUR 333
Immunoglobulin G ELISA Kit
DEIA084J 96T
EUR 627
Description: The kit is a highly sensitive twosite enzyme linked immunoassay (ELISA) for measuring IgG in Human biological samples.
Immunoglobulin G1 (IgG1) Antibody
20-abx009122
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.
Immunoglobulin A (IgA) Antibody
abx018247-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin A (IgA) Antibody
abx018248-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin A (IgA) Antibody
abx018249-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin M (IgM) Antibody
abx018250-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin M (IgM) Antibody
abx018251-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin G (IgG) Antibody
abx018252-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin G (IgG) Antibody
abx018253-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin G (IgG) Antibody
abx018254-100ug 100 ug
EUR 384
  • Shipped within 5-10 working days.
Immunoglobulin G2a (IgG2a) Antibody
20-abx178988
  • EUR 1344.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin G2a (IgG2a) Antibody
20-abx178990
  • EUR 495.00
  • EUR 133.00
  • EUR 1469.00
  • EUR 690.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin G2a (IgG2a) Antibody
20-abx178991
  • EUR 495.00
  • EUR 133.00
  • EUR 1469.00
  • EUR 690.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin G2b (IgG2b) Antibody
20-abx178992
  • EUR 1344.00
  • EUR 634.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin G2b (IgG2b) Antibody
20-abx178993
  • EUR 467.00
  • EUR 133.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin A (IgA) Antibody
20-abx216165
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.
Immunoglobulin A (IgA) Antibody
20-abx176899
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin A (IgA) Antibody
20-abx176900
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin A (IgA) Antibody
20-abx176901
  • EUR 425.00
  • EUR 133.00
  • EUR 1219.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin A (IgA) Antibody
20-abx176902
  • EUR 1288.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin A1 (IgA1) Antibody
20-abx176903
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Immunoglobulin A2 (IgA2) Antibody
20-abx176904
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin D (IgD) Antibody
20-abx176907
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin D (IgD) Antibody
20-abx176908
  • EUR 1149.00
  • EUR 565.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin E (IgE) Antibody
20-abx176909
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin E (IgE) Antibody
20-abx176910
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin E (IgE) Antibody
20-abx176911
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin E (IgE) Antibody
20-abx176912
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Immunoglobulin E (IgE) Antibody
20-abx176913
  • EUR 453.00
  • EUR 133.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Immunoglobulin G1 (IgG1) Antibody
20-abx176914
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin G1 (IgG1) Antibody
20-abx176915
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin G1 (IgG1) Antibody
20-abx176916
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin G1 (IgG1) Antibody
20-abx176917
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin G2 (IgG2) Antibody
20-abx176918
  • EUR 1302.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.
Immunoglobulin G3 (IgG3) Antibody
20-abx176919
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin G4 (IgG4) Antibody
20-abx176920
  • EUR 398.00
  • EUR 133.00
  • EUR 1094.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Immunoglobulin Kappa (Igk) Antibody
20-abx176921
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Вирус Эбола (представитель рода Ebolavirus семейства Filoviridae) является этиологическим агентом особо опасного заболевания, летальность которого достигает 90%.
  • Важнейшими компонентами спектра средств экстренной профилактики и лечения заболевания, вызванного вирусом Эбола, являются препараты на основе вирусспецифических антител (плазма реконвалесцентов, гетерологичные иммуноглобулины, моноклональные антитела).
  • Целью настоящего обзора является анализ эффективности медицинских средств защиты на основе вирусспецифических антител для экстренной профилактики и лечения заболевания, вызванного вирусом Эбола. В обзоре рассмотрено использование различных классов препаратов на основе вирусспецифических антител и возможное
  • совершенствование их состава и стратегии применения при экстренной профилактике и лечении заболевания, вызванного вирусом Эбола.
Key phrases: Ebola virus; convalescent’s plasma of blood; geterologic immunoglobulin; hemorrhagic fever; monoclonal antibodies; particular prophylactic and present; particular antibodies.

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