SARS-CoV-2 neutralizing antibody development strategies

SARS-CoV-2 neutralizing antibody development strategies

In December 2019 a novel coronavirus was detected in Wuhan Metropolis of Hubei Province-China. Owing to a excessive charge of transmission from human to human, the brand new virus known as SARS-CoV-2 differed from others by its unexpectedly fast unfold. The World Well being Group (WHO) described the latest coronavirus epidemic as a world pandemic in March 2020. The virus unfold triggered a well being disaster (the COVID-19 illness) inside three months, with socioeconomic implications.

Mouse Monoclonal Antibody

28298-100Tests 100 Tests
EUR 499

Mouse Monoclonal Antibody

28298-25Tests 25 Tests
EUR 245

Mouse Monoclonal antibody AntiCCND2

CCND2ACMO 0,1 mg
EUR 349

EFHD1 Mouse Monoclonal Antibody

38043-100ul 100ul
EUR 252

EFHD1 Mouse Monoclonal Antibody

38043-50ul 50ul
EUR 187

HSV Mouse Monoclonal Antibody

38056-100ul 100ul
EUR 252

HSV Mouse Monoclonal Antibody

38056-50ul 50ul
EUR 187

HSP90β Mouse Monoclonal Antibody

38066-100ul 100ul
EUR 252

HSP90β Mouse Monoclonal Antibody

38066-50ul 50ul
EUR 187

PARP Mouse Monoclonal Antibody

38067-100ul 100ul
EUR 252

PARP Mouse Monoclonal Antibody

38067-50ul 50ul
EUR 187

EGFR Mouse Monoclonal Antibody

38070-100ul 100ul
EUR 252

EGFR Mouse Monoclonal Antibody

38070-50ul 50ul
EUR 187

eIF4A1 Mouse Monoclonal Antibody

38072-100ul 100ul
EUR 252

eIF4A1 Mouse Monoclonal Antibody

38072-50ul 50ul
EUR 187

Fibronectin Mouse Monoclonal Antibody

38073-100ul 100ul
EUR 252

Fibronectin Mouse Monoclonal Antibody

38073-50ul 50ul
EUR 187

mStrawberry Mouse Monoclonal Antibody

38099-100ul 100ul
EUR 252

mStrawberry Mouse Monoclonal Antibody

38099-50ul 50ul
EUR 187

eNOS Mouse Monoclonal Antibody

38100-100ul 100ul
EUR 252
No authorised targeted-therapies can be found for COVID-19, but. Nonetheless, it’s foreseen that antibody-based remedies could present a direct remedy for sufferers. Present neutralizing antibody improvement research primarily goal the S protein among the many structural parts of SARS-CoV-2, which mediates the cell entry of the virus via the angiotensin changing enzyme 2 (ACE2) receptor of host cells.
gentaurprices
Gentaurprices
This evaluate goals to supply a number of the neutralizing antibody improvement methods for SARS-CoV-2 and in vitro and in vivo neutralization assays.
Key phrases: COVID-19; SARS-CoV-2; animal fashions; show applied sciences; human monoclonal antibody; human scFv; neutralizing antibodies; neutralizing assays.

Antibody Responses after Classroom Publicity to Instructor with Coronavirus Illness, March 2020

After getting back from Europe to the USA, on March 1, 2020, a symptomatic trainer obtained constructive check outcomes for extreme acute respiratory syndrome coronavirus 2. Of the 21 college students uncovered to the trainer within the classroom, serologic outcomes recommended previous an infection for two.Classroom contact could end in virus transmission.
Key phrases: 2019 novel coronavirus illness; COVID-19; SARS-CoV-2; United States; adolescents; classroom; coronavirus illness; respiratory infections; extreme acute respiratory syndrome coronavirus 2; trainer; viruses; zoonoses.

Virus particular antibody – primarily based cures for the pressing prevention and remedy of Ebola virus illness

The Ebola virus (member of Ebolavirus genus Filoviridae household) is the etiologic agent of extraordinarily hazard human illness with excessive mortality charges (as much as 90%). A very powerful parts of spectrum of therapeutics for particular prophylactic and present of illness, attributable to Ebola virus, are prepares, primarily based on virus particular antibodies (convalescent’s plasma, geterologic immunoglobulins, monoclonal antibodies.
The usage of completely different class therapeutics, primarily based on virus particular antibodies, the potential enhancements of its composition and technique of its utility for particular prophylactic and present of illness, attributable to Ebola virus, are thought-about on this evaluate.
Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280
anti- immunoglobulin kappa antibody
FNab04295 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:20-1:200
  • Immunogen: immunoglobulin kappa locus
  • Gene ID: 50802
  • Research Area: Immunology
Description: Antibody raised against immunoglobulin kappa
Anti-immunoglobulin kappa antibody
PAab04295 100 ug
EUR 386
Anti-hRPP20 Immunoglobulin antibody
STJ16100943 100 µg
EUR 892
Anti-hRRP4 Immunoglobulin antibody
STJ16100944 100 µg
EUR 892
Anti-Human Immunoglobulin IgA antibody
STJ16100584 1 mL
EUR 530
Anti-Human Immunoglobulin IgE antibody
STJ16100585 1 mL
EUR 530
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100950 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100951 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100952 100 µg
EUR 995
Anti-Citrullinated Fibrinogen Immunoglobulin antibody
STJ16100954 100 µg
EUR 1310
Anti-Polymeric immunoglobulin receptor/PIGR Antibody
A01624 100ug/vial
EUR 294
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-10x96wellstestplate 10x96-wells test plate
EUR 5386
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-1x48wellstestplate 1x48-wells test plate
EUR 531.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-1x96wellstestplate 1x96-wells test plate
EUR 716
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
AEA546Hu-5x96wellstestplate 5x96-wells test plate
EUR 2922
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Anti-Immunoglobulin A Antibody (Anti-IgA) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-A
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in serum, plasma and other biological fluids.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
4-AEA546Hu
  • EUR 5437.00
  • EUR 2873.00
  • EUR 717.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Immunoglobulin A elisa. Alternative names of the recognized antigen: n/a
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Immunoglobulin A Antibody (Anti-IgA) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
20-abx150684
  • EUR 7504.00
  • EUR 3996.00
  • EUR 926.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) ELISA Kit
abx052587-96tests 96 tests
EUR 668
  • Shipped within 5-10 working days.
Human Anti-Immunoglobulin A Antibody (Anti-IgA) CLIA Kit
20-abx490647
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 20 working days.
Human Anti-Immunoglobulin A Antibody ELISA Kit (Anti-IgA)
RK00894 96 Tests
EUR 521
immunoglobulin Kappa (immunoglobulin kappa) Antibody
abx234295-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.
Mouse Anti Rat Immunoglobulin A Monoclonal Antibody
DMABT-49896MR 0.5 mg
EUR 892
Human Anti-Immunoglobulin Binding Protein antibody(BIP)
QY-E05388 96T
EUR 361
Anti-Chicken IgG Heavy Chain Immunoglobulin antibody
STJ16100953 100 µg
EUR 474
ELISA kit for Human Anti-IgA (Anti-Immunoglobulin A Antibody)
ELK8046 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antigen. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated secondary antibody. After TMB substrate soluti
  • Show more
Description: A competitive Inhibition ELISA kit for detection of Anti-Immunoglobulin A Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Anti-Immunoglobulin A Antibody ELISA Kit (Human) (OKCD01288)
OKCD01288 96 Wells
EUR 936
Description: Description of target: Anti-Immunoglobulin A antibody;Species reactivity: Human;Application: ;Assay info: Assay Method: Quantitative Reverse Capture Sandwich ELISA;Sensitivity: 2.59 ng/mL
Human Anti-Tuberculous Glycolipid Immunoglobulin G(anti-TBGL-IgG)ELISA kit
QY-E05511 96T
EUR 361
Mouse anti-Rabbit Immunoglobulin Light Chain (IGL) Antibody (HRP)
abx401391-05ml 0.5 ml
EUR 495
  • Shipped within 1 week.
Yolk Immunoglobulin Antibody
abx110397-500ug 500 ug
EUR 300
  • Shipped within 5-10 working days.
Immunoglobulin (IG) Antibody
abx024071-200ug 200 ug
EUR 843
  • Shipped within 5-10 working days.
Immunoglobulin J Protein
20-abx261047
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.
IgG Immunoglobulin(IG217) Antibody
BNC610217-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG217), CF660R conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC610217-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG217), CF660R conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC610260-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM260), CF660R conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC610260-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM260), CF660R conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC610266-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG266), CF660R conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC610266-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG266), CF660R conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC610373-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM373), CF660R conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC610373-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM373), CF660R conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC610761-100 100uL
EUR 199
Description: Primary antibody against IgA Immunoglobulin(IA761), CF660R conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC610761-500 500uL
EUR 544
Description: Primary antibody against IgA Immunoglobulin(IA761), CF660R conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC680217-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG217), CF568 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC680217-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG217), CF568 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC680260-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM260), CF568 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC680260-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM260), CF568 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC680266-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG266), CF568 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC680266-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG266), CF568 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC680373-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM373), CF568 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC680373-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM373), CF568 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC400373-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM373), CF640R conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC400373-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM373), CF640R conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC400761-100 100uL
EUR 199
Description: Primary antibody against IgA Immunoglobulin(IA761), CF640R conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC400761-500 500uL
EUR 544
Description: Primary antibody against IgA Immunoglobulin(IA761), CF640R conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC430217-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG217), CF543 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC430217-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG217), CF543 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC430260-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM260), CF543 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC430260-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM260), CF543 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC430266-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG266), CF543 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG266) Antibody
BNC430266-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG266), CF543 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC430373-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM373), CF543 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM373) Antibody
BNC430373-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM373), CF543 conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC430761-100 100uL
EUR 199
Description: Primary antibody against IgA Immunoglobulin(IA761), CF543 conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC430761-500 500uL
EUR 544
Description: Primary antibody against IgA Immunoglobulin(IA761), CF543 conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC470761-100 100uL
EUR 199
Description: Primary antibody against IgA Immunoglobulin(IA761), CF647 conjugate, Concentration: 0.1mg/mL
IgA Immunoglobulin(IA761) Antibody
BNC470761-500 500uL
EUR 544
Description: Primary antibody against IgA Immunoglobulin(IA761), CF647 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC550217-100 100uL
EUR 199
Description: Primary antibody against IgG Immunoglobulin(IG217), CF555 conjugate, Concentration: 0.1mg/mL
IgG Immunoglobulin(IG217) Antibody
BNC550217-500 500uL
EUR 544
Description: Primary antibody against IgG Immunoglobulin(IG217), CF555 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC550260-100 100uL
EUR 199
Description: Primary antibody against IgM Immunoglobulin(IM260), CF555 conjugate, Concentration: 0.1mg/mL
IgM Immunoglobulin(IM260) Antibody
BNC550260-500 500uL
EUR 544
Description: Primary antibody against IgM Immunoglobulin(IM260), CF555 conjugate, Concentration: 0.1mg/mL
Вирус Эбола (представитель рода Ebolavirus семейства Filoviridae) является этиологическим агентом особо опасного заболевания, летальность которого достигает 90%.
  • Важнейшими компонентами спектра средств экстренной профилактики и лечения заболевания, вызванного вирусом Эбола, являются препараты на основе вирусспецифических антител (плазма реконвалесцентов, гетерологичные иммуноглобулины, моноклональные антитела).
  • Целью настоящего обзора является анализ эффективности медицинских средств защиты на основе вирусспецифических антител для экстренной профилактики и лечения заболевания, вызванного вирусом Эбола. В обзоре рассмотрено использование различных классов препаратов на основе вирусспецифических антител и возможное
  • совершенствование их состава и стратегии применения при экстренной профилактике и лечении заболевания, вызванного вирусом Эбола.
Key phrases: Ebola virus; convalescent’s plasma of blood; geterologic immunoglobulin; hemorrhagic fever; monoclonal antibodies; particular prophylactic and present; particular antibodies.

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