A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients

Background: Circulating tumor cells (CTCs) present in peripheral blood can be utilized to foretell the prognosis and survival of most cancers sufferers. The research was designed to detect circulating tumor cells and circulating tumor single cell genes by making use of microfluidic chip expertise. It was used to discover the medical utility worth in breast most cancers.

Strategies: We now have developed a size-based CTCs sorting microfluidic chip, which comprises a hexagonal array and a micro-pipe channel array to isolate and make sure each single CTCs and CTCs clusters. The sorting efficiency of the as-fabricated chip was examined by analyzing the medical samples collected from 129 breast most cancers sufferers and 50 wholesome individuals.

Outcomes: On this research, the chip can detect completely different immunophenotypes of CTCs in breast most cancers sufferers. It was discovered that the brand new microfluidic gadget had excessive sensitivity (73.6%) and specificity (82.0%) in detecting CTCs. By detecting the blood samples of 129 breast most cancers sufferers and 50 wholesome blood donors, it was discovered that the variety of CTCs was not related to medical components corresponding to age, gender, pathological kind, and tumor measurement of breast most cancers sufferers (P > 0.05), however was related to TNM staging of breast most cancers, with or with out metastasis (P < 0.005). There was a statistically vital distinction within the variety of CTCs between luminal A and HER-2+ (ER-/PR-/HER2+) (P < 0.05). The finest cut-off degree distinguished by CTC between the breast most cancers sufferers and the wholesome individuals was 3.5 cells/mL, with 0.845 for for sensitivity, and 82% for specificity. The mix of CTC, CEA, CA125 and CA153 can present simpler breast most cancers screening.

Conclusions: The CTCs evaluation methodology introduced right here does not depend on the particular antibody, corresponding to anti-EpCAM, which might keep away from the missed inspection brought on by antibody-relied strategies and provide extra complete organic data for medical breast most cancers analysis and remedy.

Zoo animals as sentinels for Schmallenberg virus monitoring in Spain

Schmallenberg virus (SBV) is a newly emerged vector-borne pathogen that impacts many home and wild animal species. A serosurvey was carried out to evaluate SBV publicity in zoo animals in Spain and to find out the dynamics of seropositivity in longitudinally sampled people. Between 2002 and 2019, sera from 278 animals belonging to 73 completely different species have been collected from 5 zoos (A-E). Thirty-one of those animals have been longitudinally sampled at three of those zoo parks in the course of the research interval. Seropositivity was detected in 28 (10.1 %) of 278 animals analyzed by blocking ELISA.

Particular anti-SBV antibodies have been confirmed in 20 animals of six completely different species utilizing virus neutralization check (VNT). The a number of logistic regression mannequin confirmed that “order” (Artiodactyla) and “zoo provenance” (zoo B; southern Spain) have been danger components probably related to SBV publicity. Two (8.7 %) of the 31 longitudinally-sampled people confirmed particular antibodies in opposition to SBV in any respect samplings whereas seroconversion was detected in a single mouflon (Ovis aries musimon) and one Asian elephant (Elephas maximus) in 2016 and 2019, respectively. To the finest of the writer’s data, that is the primary surveillance carried out on SBV in zoos in Spain.

The outcomes affirm SBV publicity in zoo animals on this nation and point out circulation of the virus earlier than the primary Schmallenberg illness outbreak was reported in Spain. Surveillance in zoological parks could possibly be a complementary method to monitoring SBV exercise. Additional research are warranted to evaluate the influence of this virus on the well being standing of inclined zoo animals.

The Community of Inflammatory Mechanisms in Lupus Nephritis

A number of signaling pathways are concerned within the development of kidney illness in people and in animal fashions, and kidney illness is often because of the sustained activation of those pathways. Among the finest understood pathways are particular proinflammatory cytokine and protein kinase pathways (e.g., protein kinase C and mitogen-activated kinase pathways, which trigger cell proliferation and fibrosis and are related to angiotensin II) and reworking development factor-beta (TGF-β) signaling pathways (e.g., the TGF-β signaling pathway, which ends up in elevated fibrosis and kidney scarring.

It’s thus essential to proceed to advance our data of the pathogenesis and molecular biology of kidney illness and to develop new remedies. This evaluate offers an replace of necessary findings about kidney illnesses (together with diabetic nephropathy, lupus nephritis, and vasculitis, i.e., vasculitis with antineutrophilic cytoplasmic antibodies). New illness targets, potential pathological pathways, and promising therapeutic approaches from fundamental science to medical follow are introduced, and the blocking of JAK/STAT and TIM-1/TIM-Four signaling pathways as potential novel therapeutic brokers in lupus nephritis is mentioned.

McArdle illness is a uncommon autosomal recessive dysfunction of muscle glycogen metabolism that presents with ache and fatigue throughout train. Stiff-Particular person Syndrome is an autoimmune-related neurologic course of characterised by fluctuating muscle rigidity and spasm. Reported is a 41-year-old male who introduced to the emergency division resulting from sudden-onset weak point and chest ache whereas transferring his fridge at house. Cardiac workup was non-contributory, however a creatine kinase degree > 6,000 warranted a muscle biopsy.

Rat Hsp60 ELISA Kit

ERH0015 96Tests
EUR 625.2

Rabbit Hsp60 ELISA Kit

ERTH0015 96Tests
EUR 625.2

Porcine Hsp60 ELISA Kit

EPH0015 96Tests
EUR 625.2

Human Hsp60 ELISA kit

55R-IB09639 96 wells
EUR 1513.2
Description: ELISA kit for the detection of Hsp60  in the research laboratory

Goat Hsp60 ELISA Kit

EGTH0015 96Tests
EUR 625.2

Bovine Hsp60 ELISA Kit

EBH0015 96Tests
EUR 625.2

Canine Hsp60 ELISA Kit

ECH0015 96Tests
EUR 625.2

Chicken Hsp60 ELISA Kit

ECKH0015 96Tests
EUR 625.2

Anserini Hsp60 ELISA Kit

EAH0015 96Tests
EUR 625.2

Human Helicobacter pylori-Hsp60,HP-HSP60 ELISA kit

201-12-1346 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Helicobacter pylori-Hsp60(HP-HSP60)ELISA Kit

GA-E1362HM-48T 48T
EUR 346.8

Human Helicobacter pylori-Hsp60(HP-HSP60)ELISA Kit

GA-E1362HM-96T 96T
EUR 559.2

Human Helicobacter pylori-Hsp60(HP-HSP60)ELISA Kit

QY-E00411 96T
EUR 433.2

Mouse HP-HSp60 ELISA Kit

EMH0274 96Tests
EUR 625.2

Sheep HP-HSp60 ELISA Kit

ESH0274 96Tests
EUR 625.2

Human HP-HSp60 ELISA Kit

EHH0274 96Tests
EUR 625.2

Monkey HP-HSp60 ELISA Kit

EMKH0274 96Tests
EUR 625.2

Rat HP-HSp60 ELISA Kit

ERH0274 96Tests
EUR 625.2

Rabbit HP-HSp60 ELISA Kit

ERTH0274 96Tests
EUR 625.2

Porcine HP-HSp60 ELISA Kit

EPH0274 96Tests
EUR 625.2

Goat HP-HSp60 ELISA Kit

EGTH0274 96Tests
EUR 625.2

Bovine HP-HSp60 ELISA Kit

EBH0274 96Tests
EUR 625.2

Canine HP-HSp60 ELISA Kit

ECH0274 96Tests
EUR 625.2

Chicken HP-HSp60 ELISA Kit

ECKH0274 96Tests
EUR 625.2

Guinea Pig Hsp60 ELISA Kit

EGH0015 96Tests
EUR 625.2

Nori Equine HSP60 ELISA Kit

GR106534 96-well
EUR 553.2

Nori Human HSP60 ELISA Kit

GR111055 96-well
EUR 553.2

Nori Porcine HSP60 ELISA Kit

GR113017 96-well
EUR 553.2

Anserine HP-HSp60 ELISA Kit

EAH0274 96Tests
EUR 625.2

HSP60

CH22117 100 ul
EUR 522

HSP60

MO15152 100 ug
EUR 669.6

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Human Helicobacter pylori Hsp60 ELISA kit

E01H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Helicobacter pylori Hsp60 ELISA kit

E01H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Helicobacter pylori Hsp60 ELISA kit

E01H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Hsp60 antibody(IgG) ELISA kit

CSB-E13499h-24T 1 plate of 24 wells
EUR 198
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 antibody(IgG) ELISA kit

1-CSB-E13499h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody(IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Hsp60 antibody(IgM) ELISA kit

CSB-E13500h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody (IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 antibody(IgM) ELISA kit

1-CSB-E13500h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody(IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Hsp60 IgA antibody ELISA kit

CSB-E13501h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 IgA antibody ELISA kit

1-CSB-E13501h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Goat Helicobacter pylori Hsp60 ELISA kit

E06H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Helicobacter pylori Hsp60 ELISA kit

E06H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Helicobacter pylori Hsp60 ELISA kit

E06H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit

E08H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit

E08H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit

E08H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit

E04H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit

E04H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit

E04H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Helicobacter pylori Hsp60 ELISA kit

E07H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Helicobacter pylori Hsp60 ELISA kit

E07H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Helicobacter pylori Hsp60 ELISA kit

E07H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Helicobacter pylori Hsp60 ELISA kit

E03H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Helicobacter pylori Hsp60 ELISA kit

E03H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Helicobacter pylori Hsp60 ELISA kit

E03H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit

E02H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit

E02H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit

E02H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit

E09H0267-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit

E09H0267-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit

E09H0267-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig HP-HSp60 ELISA Kit

EGH0274 96Tests
EUR 625.2

Nori® Zebrafish HSP60 ELISA Kit

GR206149 96-well
EUR 553.2

Nori® Rabbit HSP60 ELISA Kit

GR144343 96-well
EUR 553.2

Nori® Monkey HSP60 ELISA Kit

GR169317 96-well
EUR 553.2

Nori® Hamster HSP60 ELISA Kit

GR172301 96-well
EUR 553.2

Nori® Feline HSP60 ELISA Kit

GR188252 96-well
EUR 553.2

Nori® Ferret HSP60 ELISA Kit

GR201149 96-well
EUR 553.2

Nori® Salmon HSP60 ELISA Kit

GR202149 96-well
EUR 553.2

Nori® Chicken HSP60 ELISA Kit

GR114260 96-well
EUR 553.2

Nori® Canine HSP60 ELISA Kit

GR115057 96-well
EUR 553.2

Nori® Sheep HSP60 ELISA Kit

GR116366 96-well
EUR 553.2

Nori® Mouse HSP60 ELISA Kit

GR117378 96-well
EUR 553.2

Nori® Rat HSP60 ELISA Kit

GR118361 96-well
EUR 553.2

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 319.2

HSP60 Antibody

DF6151 200ul
EUR 420

HSP60 Antibody

AF5374 200ul
EUR 420

HSP60 Antibody

AF6732 100ul
EUR 420

HSP60 Antibody

AF0184 200ul
EUR 420

HSP60 antibody

70R-49878 100 ul
EUR 292.8
Description: Purified Polyclonal HSP60 antibody

Hsp60 Antibody

48882-100ul 100ul
EUR 399.6

Hsp60 Antibody

48882-50ul 50ul
EUR 286.8

Hsp60 antibody

70R-11609 100 ug
EUR 483.6
Description: Rabbit polyclonal Hsp60 antibody

HSP60 antibody

70R-13771 100 ug
EUR 386.4
Description: Affinity purified Rabbit polyclonal HSP60 antibody

hsp60 Antibody

39380-100ul 100ul
EUR 468

Hsp60 Antibody

3094R-100
EUR 379.2

Hsp60 Antibody

3094R-30T
EUR 175.2

HSP60 antibody

10R-7862 100 ug
EUR 386.4
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

20R-1449 100 ug
EUR 807.6
Description: Rabbit polyclonal HSP60 antibody

HSP60 antibody

10R-10500 100 ug
EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

10R-10501 100 ug
EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

10R-10502 100 ug
EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

10R-10598 100 ug
EUR 418.8
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

10R-10601 100 ug
EUR 418.8
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody

10R-1076 100 ul
EUR 379.2
Description: Mouse monoclonal HSP60 antibody

HSP60 Antibody

33408-100ul 100ul
EUR 302.4

HSP60 Antibody

33408-50ul 50ul
EUR 224.4

Hsp60 antibody

10-2295 100 ug
EUR 489.6
Description: Recombinant Fab monoclonal Hsp60 antibody

Hsp60 antibody

10-2296 100 ug
EUR 489.6
Description: Recombinant Fab monoclonal Hsp60 antibody

HSP60 Antibody

ABF0184 100 ug
EUR 525.6

HSP60 Antibody

ABF5374 100 ug
EUR 525.6

HSP60 protein

E20-80044 20ug
EUR 489.6

HSP60 (D307)

RA18029 100 ul
EUR 666

HSP60 (D85)

RA18030 100 ul
EUR 579.6

anti-Hsp60

YF-PA12493 50 ul
EUR 435.6
Description: Mouse polyclonal to Hsp60

anti-Hsp60

YF-PA12494 50 ug
EUR 435.6
Description: Mouse polyclonal to Hsp60

anti-Hsp60

YF-PA12495 100 ul
EUR 483.6
Description: Rabbit polyclonal to Hsp60

anti-Hsp60

YF-PA12496 100 ug
EUR 483.6
Description: Rabbit polyclonal to Hsp60

HSP60 Antibody

R30272 100 ug
EUR 419

HSP60 Antibody

R31750 100 ug
EUR 419

HSP60 Antibody

R36413-100UG 100 ug
EUR 399

HSP60 Antibody

RQ5336 100ul
EUR 419

HSP60 Antibody

RQ5508 100 ug
EUR 419

HSP60 Antibody

V7849-100UG 100 ug
EUR 499
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.

HSP60 Antibody

V7849-20UG 20 ug
EUR 219
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.

HSP60 Antibody

V7849SAF-100UG 100 ug
EUR 499
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.

HSP60 Antibody

F49879-0.08ML 0.08 ml
EUR 165

HSP60 Antibody

F49879-0.4ML 0.4 ml
EUR 379

HSP60 Antibody

F54325-0.05ML 0.05 ml
EUR 165

HSP60 Antibody

F54325-0.2ML 0.2 ml
EUR 379

HSP60 Antibody

F54512-0.05ML 0.05 ml
EUR 165

HSP60 Antibody

F54512-0.2ML 0.2 ml
EUR 379

HSP60 Antibody

V2136-100UG 100 ug
EUR 499
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

HSP60 Antibody

V2136-20UG 20 ug
EUR 219
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

HSP60 Antibody

V2136IHC-7ML 7 ml
EUR 499
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

HSP60 Antibody

V2136SAF-100UG 100 ug
EUR 499
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.

HSP60 Antibody

V2137-100UG 100 ug
EUR 499
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.

HSP60 Antibody

V2137-20UG 20 ug
EUR 219
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.

HSP60 Antibody

V2137SAF-100UG 100 ug
EUR 499
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.

HSP60 Antibody

V2594-100UG 100 ug
EUR 499
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (Hsp60). Its epitope is localized between amino acids 383-447 of human Hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial Hsp60, but also against its mammalian homolog.

The biopsy pathology report was misinterpreted to be diagnostic for McArdle illness given the medical presentation. After Four years of remedy with out symptomatic enchancment, a gradual transition of signs from ache alone to ache with stiffness was famous.

Leave a Reply