Background: Circulating tumor cells (CTCs) present in peripheral blood can be utilized to foretell the prognosis and survival of most cancers sufferers. The research was designed to detect circulating tumor cells and circulating tumor single cell genes by making use of microfluidic chip expertise. It was used to discover the medical utility worth in breast most cancers.

Strategies: We now have developed a size-based CTCs sorting microfluidic chip, which comprises a hexagonal array and a micro-pipe channel array to isolate and make sure each single CTCs and CTCs clusters. The sorting efficiency of the as-fabricated chip was examined by analyzing the medical samples collected from 129 breast most cancers sufferers and 50 wholesome individuals.

Outcomes: On this research, the chip can detect completely different immunophenotypes of CTCs in breast most cancers sufferers. It was discovered that the brand new microfluidic gadget had excessive sensitivity (73.6%) and specificity (82.0%) in detecting CTCs. By detecting the blood samples of 129 breast most cancers sufferers and 50 wholesome blood donors, it was discovered that the variety of CTCs was not related to medical components corresponding to age, gender, pathological kind, and tumor measurement of breast most cancers sufferers (P > 0.05), however was related to TNM staging of breast most cancers, with or with out metastasis (P < 0.005). There was a statistically vital distinction within the variety of CTCs between luminal A and HER-2+ (ER-/PR-/HER2+) (P < 0.05). The finest cut-off degree distinguished by CTC between the breast most cancers sufferers and the wholesome individuals was 3.5 cells/mL, with 0.845 for for sensitivity, and 82% for specificity. The mix of CTC, CEA, CA125 and CA153 can present simpler breast most cancers screening.

Conclusions: The CTCs evaluation methodology introduced right here does not depend on the particular antibody, corresponding to anti-EpCAM, which might keep away from the missed inspection brought on by antibody-relied strategies and provide extra complete organic data for medical breast most cancers analysis and remedy.

Zoo animals as sentinels for Schmallenberg virus monitoring in Spain

Schmallenberg virus (SBV) is a newly emerged vector-borne pathogen that impacts many home and wild animal species. A serosurvey was carried out to evaluate SBV publicity in zoo animals in Spain and to find out the dynamics of seropositivity in longitudinally sampled people. Between 2002 and 2019, sera from 278 animals belonging to 73 completely different species have been collected from 5 zoos (A-E). Thirty-one of those animals have been longitudinally sampled at three of those zoo parks in the course of the research interval. Seropositivity was detected in 28 (10.1 %) of 278 animals analyzed by blocking ELISA.

Particular anti-SBV antibodies have been confirmed in 20 animals of six completely different species utilizing virus neutralization check (VNT). The a number of logistic regression mannequin confirmed that “order” (Artiodactyla) and “zoo provenance” (zoo B; southern Spain) have been danger components probably related to SBV publicity. Two (8.7 %) of the 31 longitudinally-sampled people confirmed particular antibodies in opposition to SBV in any respect samplings whereas seroconversion was detected in a single mouflon (Ovis aries musimon) and one Asian elephant (Elephas maximus) in 2016 and 2019, respectively. To the finest of the writer’s data, that is the primary surveillance carried out on SBV in zoos in Spain.

The outcomes affirm SBV publicity in zoo animals on this nation and point out circulation of the virus earlier than the primary Schmallenberg illness outbreak was reported in Spain. Surveillance in zoological parks could possibly be a complementary method to monitoring SBV exercise. Additional research are warranted to evaluate the influence of this virus on the well being standing of inclined zoo animals.

The Community of Inflammatory Mechanisms in Lupus Nephritis

A number of signaling pathways are concerned within the development of kidney illness in people and in animal fashions, and kidney illness is often because of the sustained activation of those pathways. Among the finest understood pathways are particular proinflammatory cytokine and protein kinase pathways (e.g., protein kinase C and mitogen-activated kinase pathways, which trigger cell proliferation and fibrosis and are related to angiotensin II) and reworking development factor-beta (TGF-β) signaling pathways (e.g., the TGF-β signaling pathway, which ends up in elevated fibrosis and kidney scarring.

It’s thus essential to proceed to advance our data of the pathogenesis and molecular biology of kidney illness and to develop new remedies. This evaluate offers an replace of necessary findings about kidney illnesses (together with diabetic nephropathy, lupus nephritis, and vasculitis, i.e., vasculitis with antineutrophilic cytoplasmic antibodies). New illness targets, potential pathological pathways, and promising therapeutic approaches from fundamental science to medical follow are introduced, and the blocking of JAK/STAT and TIM-1/TIM-Four signaling pathways as potential novel therapeutic brokers in lupus nephritis is mentioned.

McArdle illness is a uncommon autosomal recessive dysfunction of muscle glycogen metabolism that presents with ache and fatigue throughout train. Stiff-Particular person Syndrome is an autoimmune-related neurologic course of characterised by fluctuating muscle rigidity and spasm. Reported is a 41-year-old male who introduced to the emergency division resulting from sudden-onset weak point and chest ache whereas transferring his fridge at house. Cardiac workup was non-contributory, however a creatine kinase degree > 6,000 warranted a muscle biopsy.

Human Hsp60 ELISA Kit
EHH0015	Abclonal	96Tests	EUR 625.2

Rabbit Hsp60 ELISA Kit
ERTH0015	Abclonal	96Tests	EUR 625.2

Monkey Hsp60 ELISA Kit
EMKH0015	Abclonal	96Tests	EUR 625.2

Bovine Hsp60 ELISA Kit
EBH0015	Abclonal	96Tests	EUR 625.2

Canine Hsp60 ELISA Kit
ECH0015	Abclonal	96Tests	EUR 625.2

Porcine Hsp60 ELISA Kit
EPH0015	Abclonal	96Tests	EUR 625.2

Chicken Hsp60 ELISA Kit
ECKH0015	Abclonal	96Tests	EUR 625.2

Anserini Hsp60 ELISA Kit
EAH0015	Abclonal	96Tests	EUR 625.2

Nori Human HSP60 ELISA Kit
GR111055	Genorise Scientific	96-well	EUR 461

Guinea Pig Hsp60 ELISA Kit
EGH0015	Abclonal	96Tests	EUR 625.2

Nori Equine HSP60 ELISA Kit
GR106534	Genorise Scientific	96-well	EUR 461

Nori Porcine HSP60 ELISA Kit
GR113017	Genorise Scientific	96-well	EUR 461

Nori® Rat HSP60 ELISA Kit
GR118361	Genorise Scientific	96-well	EUR 461

Nori® Sheep HSP60 ELISA Kit
GR116366	Genorise Scientific	96-well	EUR 461

Nori® Mouse HSP60 ELISA Kit
GR117378	Genorise Scientific	96-well	EUR 461

Nori® Ferret HSP60 ELISA Kit
GR201149	Genorise Scientific	96-well	EUR 461

Nori® Salmon HSP60 ELISA Kit
GR202149	Genorise Scientific	96-well	EUR 461

Nori® Feline HSP60 ELISA Kit
GR188252	Genorise Scientific	96-well	EUR 461

Nori® Rabbit HSP60 ELISA Kit
GR144343	Genorise Scientific	96-well	EUR 461

Nori® Monkey HSP60 ELISA Kit
GR169317	Genorise Scientific	96-well	EUR 461

Nori® Canine HSP60 ELISA Kit
GR115057	Genorise Scientific	96-well	EUR 461

Nori® Hamster HSP60 ELISA Kit
GR172301	Genorise Scientific	96-well	EUR 461

Nori® Chicken HSP60 ELISA Kit
GR114260	Genorise Scientific	96-well	EUR 461

Nori® Zebrafish HSP60 ELISA Kit
GR206149	Genorise Scientific	96-well	EUR 461

Pig Helicobacter pylori Hsp60 ELISA kit
E07H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Helicobacter pylori Hsp60 ELISA kit
E07H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Helicobacter pylori Hsp60 ELISA kit
E07H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit
E08H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit
E08H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Helicobacter pylori Hsp60 ELISA kit
E08H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit
E02H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit
E02H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Helicobacter pylori Hsp60 ELISA kit
E02H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Helicobacter pylori Hsp60 ELISA kit
E06H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Helicobacter pylori Hsp60 ELISA kit
E06H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Helicobacter pylori Hsp60 ELISA kit
E06H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Hsp60 antibody(IgG) ELISA kit
CSB-E13499h-24T	Cusabio	1 plate of 24 wells	EUR 198
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 antibody(IgG) ELISA kit
1-CSB-E13499h	Cusabio	EUR 1080.00 EUR 6571.20 EUR 3480.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody(IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Hsp60 antibody(IgM) ELISA kit
CSB-E13500h-24T	Cusabio	1 plate of 24 wells	EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody (IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 antibody(IgM) ELISA kit
1-CSB-E13500h	Cusabio	EUR 1080.00 EUR 6571.20 EUR 3480.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody(IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Hsp60 IgA antibody ELISA kit
CSB-E13501h-24T	Cusabio	1 plate of 24 wells	EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Hsp60 IgA antibody ELISA kit
1-CSB-E13501h	Cusabio	EUR 1080.00 EUR 6571.20 EUR 3480.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Helicobacter pylori Hsp60 ELISA kit
E03H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Helicobacter pylori Hsp60 ELISA kit
E03H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Helicobacter pylori Hsp60 ELISA kit
E03H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Helicobacter pylori Hsp60 ELISA kit
E01H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Helicobacter pylori Hsp60 ELISA kit
E01H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Helicobacter pylori Hsp60 ELISA kit
E01H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit
E04H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit
E04H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Helicobacter pylori Hsp60 ELISA kit
E04H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit
E09H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit
E09H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Helicobacter pylori Hsp60 ELISA kit
E09H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Nori Human HSP60 ELISA Kit-2 Plates
GR111055-2	Genorise Scientific	2 x 96-well	EUR 832

Nori® Guinea Pig HSP60 ELISA Kit
GR171302	Genorise Scientific	96-well	EUR 461

Nori Porcine HSP60 ELISA Kit-2 Plates
GR113017-2	Genorise Scientific	2 x 96-well	EUR 832

Human Hsp60 IgG/A/M ELISA kit
55R-IB09638	Fitzgerald	96 wells	EUR 1513.2
Description: ELISA kit for the detection of Human Hsp60 IgG/A/M in the research laboratory

HSP60 ELISA Kit| Bovine Heat shock protein 60 ELISA Kit
EF010985	Lifescience Market	96 Tests	EUR 826.8

Guinea pig Helicobacter pylori Hsp60 ELISA kit
E05H0267-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Helicobacter pylori Hsp60 ELISA kit
E05H0267-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Helicobacter pylori Hsp60 ELISA kit
E05H0267-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine HSP60(Heat shock protein 60) ELISA Kit
EB0031	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Cattle;Sensitivity: 0.938 ng/ml

Human Heat Shock Protein 60 (HSP60) AssayMax ELISA Kit
EH5505-1	AssayPro	96 Well Plate	EUR 475.2

HSP60
CH22117	Neuromics	100 ul	EUR 522

HSP60
MO15152	Neuromics	100 ug	EUR 669.6

Human Heat Shock Protein 60 IgG (HSP60 IgG) ELISA Kit
abx352296-96tests	Abbexa	96 tests	EUR 801.6

Rat Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx255728-96tests	Abbexa	96 tests	EUR 801.6

Cow Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx257482-96tests	Abbexa	96 tests	EUR 1093.2

Dog Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx514105-96tests	Abbexa	96 tests	EUR 1093.2

Rat Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx575192-96tests	Abbexa	96 tests	EUR 801.6

Pig Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx360676-96tests	Abbexa	96 tests	EUR 904.8

Mouse Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx254189-96tests	Abbexa	96 tests	EUR 801.6

Human Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx250300-96tests	Abbexa	96 tests	EUR 801.6

Sheep Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx364383-96tests	Abbexa	96 tests	EUR 1111.2

Human Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx053034-96tests	Abbexa	96 tests	EUR 801.6

Human Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx350059-96tests	Abbexa	96 tests	EUR 801.6

Rabbit Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx363404-96tests	Abbexa	96 tests	EUR 990

Monkey Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx359688-96tests	Abbexa	96 tests	EUR 904.8

Chicken Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx356118-96tests	Abbexa	96 tests	EUR 904.8

Chicken Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx570350-96tests	Abbexa	96 tests	EUR 904.8

Rat Heat Shock Protein 60 (HSP60) ELISA Kit, 96 tests, Quantitative
9450	Alpha Diagnostics	1 Kit	EUR 927.6

Mouse Heat Shock Protein 60 (HSP60) ELISA Kit, 96 tests, Quantitative
9150	Alpha Diagnostics	1 Kit	EUR 927.6

Guinea pig Heat Shock 60 kDa Protein 1 / HSP60 (HSPD1) ELISA Kit
abx357415-96tests	Abbexa	96 tests	EUR 904.8

Rat Heat Shock 60 kDa Protein 1 / HSP60 / GROEL (HSPD1) ELISA Kit
20-abx155657	Abbexa	EUR 8684.40 EUR 4626.00 EUR 1074.00	10 × 96 tests 5 × 96 tests 96 tests

Human Heat Shock 60 kDa Protein 1 / HSP60 / GROEL (HSPD1) ELISA Kit
20-abx151874	Abbexa	EUR 7970.40 EUR 4250.40 EUR 990.00	10 × 96 tests 5 × 96 tests 96 tests

Human Heat Shock 60 kDa Protein 1 / HSP60 / GROEL (HSPD1) ELISA Kit
abx259906-96well	Abbexa	96 well	EUR 1111.2

Mouse Heat Shock 60 kDa Protein 1 / HSP60 / GROEL (HSPD1) ELISA Kit
20-abx154164	Abbexa	EUR 7970.40 EUR 4250.40 EUR 990.00	10 × 96 tests 5 × 96 tests 96 tests

HSP60 (D85)
RA18030	Neuromics	100 ul	EUR 579.6

HSP60 (D307)
RA18029	Neuromics	100 ul	EUR 666

[One Step] Hsp60 Antibody Kit
RK05661	Abclonal	50 ul	EUR 288

HSP60 protein
E20-80044	EnoGene	20ug	EUR 489.6

Hsp60 antibody
10-2295	Fitzgerald	100 ug	EUR 489.6
Description: Recombinant Fab monoclonal Hsp60 antibody

Hsp60 antibody
10-2296	Fitzgerald	100 ug	EUR 489.6
Description: Recombinant Fab monoclonal Hsp60 antibody

HSP60 antibody
10R-10500	Fitzgerald	100 ug	EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-10501	Fitzgerald	100 ug	EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-10502	Fitzgerald	100 ug	EUR 522
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-10598	Fitzgerald	100 ug	EUR 418.8
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-10601	Fitzgerald	100 ug	EUR 418.8
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-1076	Fitzgerald	100 ul	EUR 379.2
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
10R-7862	Fitzgerald	100 ug	EUR 386.4
Description: Mouse monoclonal HSP60 antibody

HSP60 antibody
20R-1449	Fitzgerald	100 ug	EUR 807.6
Description: Rabbit polyclonal HSP60 antibody

Hsp60 Antibody
3094R-100	Biovision	each	EUR 379.2

Hsp60 Antibody
3094R-30T	Biovision	each	EUR 175.2

hsp60 Antibody
39380-100ul	SAB	100ul	EUR 468

HSP60 Antibody
AF0184	Affbiotech	200ul	EUR 420

HSP60 Antibody
AF5374	Affbiotech	200ul	EUR 420

HSP60 Antibody
AF6732	Affbiotech	100ul	EUR 420

Hsp60 antibody
70R-11609	Fitzgerald	100 ug	EUR 483.6
Description: Rabbit polyclonal Hsp60 antibody

HSP60 antibody
70R-13771	Fitzgerald	100 ug	EUR 386.4
Description: Affinity purified Rabbit polyclonal HSP60 antibody

HSP60 antibody
70R-49878	Fitzgerald	100 ul	EUR 292.8
Description: Purified Polyclonal HSP60 antibody

HSP60 Antibody
33408-100ul	SAB	100ul	EUR 302.4

HSP60 Antibody
33408-50ul	SAB	50ul	EUR 224.4

Hsp60 Antibody
48882-100ul	SAB	100ul	EUR 399.6

Hsp60 Antibody
48882-50ul	SAB	50ul	EUR 286.8

HSP60 Antibody
ABF0184	Lifescience Market	100 ug	EUR 525.6

HSP60 Antibody
ABF5374	Lifescience Market	100 ug	EUR 525.6

HSP60 Antibody
DF6151	Affbiotech	200ul	EUR 420

HSP60 Antibody
F54325-0.05ML	NSJ Bioreagents	0.05 ml	EUR 140.25
Description: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

HSP60 Antibody
F54325-0.2ML	NSJ Bioreagents	0.2 ml	EUR 322.15
Description: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

HSP60 Antibody
F54512-0.05ML	NSJ Bioreagents	0.05 ml	EUR 140.25
Description: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

HSP60 Antibody
F54512-0.2ML	NSJ Bioreagents	0.2 ml	EUR 322.15
Description: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

HSP60 Antibody
F49879-0.08ML	NSJ Bioreagents	0.08 ml	EUR 140.25
Description: Hsp60 is a member of a highly conserved family which includes molecular chaperones from several species such as plant Hsp60 (known as Rubisco binding protein), GroEL, the E.coli Hsp60 and 65 kDa major antigen of mycobacteria. In eukaryotes, Hsp60 is localized in the mitochondrial matrix and in plants Hsp60 is localized in the chloroplast. Mitochondria, chloroplasts and bacteria have a common ancestry (>1 billion years) and this fact together with the high degree of homology between the divegent Hsp60s would indicate that these proteins carry out a primitive but important function which is similar to all of these different species.The common characteristics of the Hsp60s from the divergent species are i) high abundance, ii) induction with environmental stress such as heat shock, iii) homo oligomeric structures of either 7 or 14 subunits which reversibly dissociate in the presence of magnesium ions and ATP, iv) ATPase activity and v) a role in folding and assembly of oligomeric protein structures. These similarities are supported by recent studies where the single ring human mitochondrial homolog, Hsp60 with its co chaperonin, Hsp10 were expressed in a E. coli strain, engineered so that the groE operon is under strict regulatory control. This study has demonstrated that expression of Hsp60-Hsp10 was able to carry out all essential in vivo functions of GroEL and its co chaperonin, GroES. Consistent with their functions as chaperones, Hsp60 and Hsp10 have been suggested to act as docking molecules with a passive role in the maturation of caspase processing. Data demonstrates that recombinant Hsp60 and Hsp10 have been shown to accelerate the activation of procaspase 3 by cytochrome c and dATP in an ATP dependent manner. Hsps are intracellular proteins which are thought to serve protective functions against infection and cellular stress, however several recent studies indicate that members of the Hsp60 family are linked to a number of autoimmune diseases, artherosclerosis and chlamydial disease.

HSP60 Antibody
F49879-0.4ML	NSJ Bioreagents	0.4 ml	EUR 322.15
Description: Hsp60 is a member of a highly conserved family which includes molecular chaperones from several species such as plant Hsp60 (known as Rubisco binding protein), GroEL, the E.coli Hsp60 and 65 kDa major antigen of mycobacteria. In eukaryotes, Hsp60 is localized in the mitochondrial matrix and in plants Hsp60 is localized in the chloroplast. Mitochondria, chloroplasts and bacteria have a common ancestry (>1 billion years) and this fact together with the high degree of homology between the divegent Hsp60s would indicate that these proteins carry out a primitive but important function which is similar to all of these different species.The common characteristics of the Hsp60s from the divergent species are i) high abundance, ii) induction with environmental stress such as heat shock, iii) homo oligomeric structures of either 7 or 14 subunits which reversibly dissociate in the presence of magnesium ions and ATP, iv) ATPase activity and v) a role in folding and assembly of oligomeric protein structures. These similarities are supported by recent studies where the single ring human mitochondrial homolog, Hsp60 with its co chaperonin, Hsp10 were expressed in a E. coli strain, engineered so that the groE operon is under strict regulatory control. This study has demonstrated that expression of Hsp60-Hsp10 was able to carry out all essential in vivo functions of GroEL and its co chaperonin, GroES. Consistent with their functions as chaperones, Hsp60 and Hsp10 have been suggested to act as docking molecules with a passive role in the maturation of caspase processing. Data demonstrates that recombinant Hsp60 and Hsp10 have been shown to accelerate the activation of procaspase 3 by cytochrome c and dATP in an ATP dependent manner. Hsps are intracellular proteins which are thought to serve protective functions against infection and cellular stress, however several recent studies indicate that members of the Hsp60 family are linked to a number of autoimmune diseases, artherosclerosis and chlamydial disease.

HSP60 Antibody
R36413-100UG	NSJ Bioreagents	100 ug	EUR 339.15
Description: Additional name(s) for this target protein: HSPD1, Heat shock 60kDa protein 1, Chaperonin, GROEL

HSP60 Antibody
R30272	NSJ Bioreagents	100 ug	EUR 356.15
Description: Heat shock 60KD protein is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. It can downregulate adaptive immune responses by upregulating Tregs innately throughTLR2signaling.

HSP60 Antibody
R31750	NSJ Bioreagents	100 ug	EUR 356.15
Description: HSP60 is a member of the chaperonin class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts. It acts as a costimulator of human regulatory CD4-positive/CD25 -positive T cells, which inhibit lymphoproliferation and IFNG and TNF secretion by CD4-positive and CD8-positive T cells. HSP60 enhances Treg activity via TLR2, leading to activation of an intracellular signaling cascade that included p38, as well as inhibition of ERK phosphorylation. Suppression of target T cells is mediated by both cell-to-cell contact and by secretion of TGFB and IL10, and it leads to downregulation of ERK, NFKB, and TBET expression. The self-molecule HSP60 can downregulate adaptive immune responses by upregulating Tregs through TLR2signaling.

HSP60 Antibody
RQ5336	NSJ Bioreagents	100ul	EUR 356.15
Description: The HSPD1 gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [RefSeq]

HSP60 Antibody
RQ5508	NSJ Bioreagents	100 ug	EUR 356.15
Description: HSP60 is a member of the chaperonin class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts. It acts as a costimulator of human regulatory CD4-positive/CD25 -positive T cells, which inhibit lymphoproliferation and IFNG and TNF secretion by CD4-positive and CD8-positive T cells. HSP60 enhances Treg activity via TLR2, leading to activation of an intracellular signaling cascade that included p38, as well as inhibition of ERK phosphorylation. Suppression of target T cells is mediated by both cell-to-cell contact and by secretion of TGFB and IL10, and it leads to downregulation of ERK, NFKB, and TBET expression. The self-molecule HSP60 can downregulate adaptive immune responses by upregulating Tregs through TLR2 signaling.

HSP60 Antibody
V3575-100UG	NSJ Bioreagents	100 ug	EUR 349.3
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]

HSP60 Antibody
V3575-20UG	NSJ Bioreagents	20 ug	EUR 153.3
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]

HSP60 Antibody
V3575IHC-7ML	NSJ Bioreagents	7 ml	EUR 349.3
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]

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