Progress in Shark Single-Area Antibody

Monoclonal antibody (mAb) is a vital organic macromolecule and broadly utilized in immune detection, in vitro diagnostics, and drug discovery. Nevertheless, the inherent properties of mAb prohibit its additional growth, akin to excessive molecular weight and complicated construction. Subsequently, there’s an pressing have to develop options for mAb. Varied kinds of miniaturized antibodies have been developed, amongst which the variable area of immunoglobulin new antigen receptor (VNAR) could be very engaging.

 

Genatur Prices
Genatur Prices

 

Maackiain

TM092356 20mg Ask for price

(-)-Maackiain

TBZ2136 20mg Ask for price

M4A4A Antibody

abx025924-400ul 400 ul
EUR 627.6

M4A4A Antibody

abx025924-80l 80 µl
EUR 343.2

MAA ORF Vector (Human) (pORF)

ORF023203 1.0 ug DNA Ask for price

MAA 3'UTR GFP Stable Cell Line

TU062822 1.0 ml
EUR 2799.6

Maackiaflavanone

TBW00511 5mg
EUR 1233.6

Mouse MAATS1 shRNA Plasmid

20-abx983374
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human MAATS1 shRNA Plasmid

20-abx963876
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

MAA Protein Vector (Human) (pPM-C-HA)

PV092812 500 ng Ask for price

MAA Protein Vector (Human) (pPB-C-His)

PV092810 500 ng Ask for price

MAA Protein Vector (Human) (pPB-N-His)

PV092811 500 ng Ask for price

MAA Protein Vector (Human) (pPM-C-His)

PV092813 500 ng Ask for price

MAA Recombinant Protein (Human)

RP069606 100 ug Ask for price

MAA 3'UTR Luciferase Stable Cell Line

TU012822 1.0 ml
EUR 2799.6

MAA sgRNA CRISPR Lentivector set (Human)

K1250401 3 x 1.0 ug
EUR 406.8

MAA sgRNA CRISPR Lentivector (Human) (Target 1)

K1250402 1.0 ug DNA
EUR 184.8

MAA sgRNA CRISPR Lentivector (Human) (Target 2)

K1250403 1.0 ug DNA
EUR 184.8

MAA sgRNA CRISPR Lentivector (Human) (Target 3)

K1250404 1.0 ug DNA
EUR 184.8

Anti-HSP47 Antibody (Monoclonal, M16.10A1)

M03050 200ug/vial
EUR 590.4
Description: Mouse Monoclonal HSP47 Antibody (Monoclonal, M16.10A1). Validated in IHC, WB and tested in Human, Mouse, Rat.

Melanoma Associated Antigen Antibody / MAA

V8899-100UG 100ug
EUR 349.3

Melanoma Associated Antigen Antibody / MAA

V8899-20UG 20ug
EUR 153.3

Melanoma Associated Antigen Antibody / MAA

V8899SAF-100UG 100ug
EUR 349.3

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732365 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV732369 1.0 ug DNA Ask for price

Trifolirhizin;(-)-Maackiain-3-O-glucoside

N1959-20 20 mg
EUR 408
Description: Extracted from Sophora flavescens;Suitability:DMSO,methanol;Store the product in sealed,cool and dry condition

MAA sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1250405 3 x 1.0 ug
EUR 451.2

MAA Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV732370 1.0 ug DNA Ask for price

MAA sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1250406 1.0 ug DNA
EUR 200.4

MAA sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1250407 1.0 ug DNA
EUR 200.4

MAA sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1250408 1.0 ug DNA
EUR 200.4

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV732366 1.0 ug DNA Ask for price

Amy1 Associated Protein Expressed In Testis (MAATS1) Antibody

20-abx216641
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV732367 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV732368 1.0 ug DNA Ask for price

Recombinant Human Maleylacetoacetate Isomerase/MAA/GSTZ1 (C-6His)

CE41-10ug 10ug
EUR 242.4
Description: Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, 1mM DTT, pH 8.0.

Recombinant Human Maleylacetoacetate Isomerase/MAA/GSTZ1 (C-6His)

CE41-1mg 1mg
EUR 2739.6
Description: Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, 1mM DTT, pH 8.0.

Recombinant Human Maleylacetoacetate Isomerase/MAA/GSTZ1 (C-6His)

CE41-500ug 500ug
EUR 1935.6
Description: Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, 1mM DTT, pH 8.0.

Recombinant Human Maleylacetoacetate Isomerase/MAA/GSTZ1 (C-6His)

CE41-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, 1mM DTT, pH 8.0.
  • The shark single-domain antibody, often known as shark VNAR, is an antigen-binding area obtained by genetic engineering expertise based mostly on the immunoglobulin new antigen receptor (IgNAR) that naturally exists in selachimorpha.

 

  • It has a molecular weight of 12 kDa, which is the smallest antigen-binding area discovered within the identified vertebrates at current. In contrast with mAb, the shark VNAR displays numerous superiorities, akin to low molecular weight, excessive affinity, tolerance to the cruel setting, good water solubility, robust tissue penetration, and recognition of the hidden epitopes.

 

It has attracted large consideration within the fields of immunochemical reagents and drug discovery. On this evaluation, numerous points of shark VNAR are elaborated, together with the structural and purposeful traits, producing and humanization strategies, affinity maturation methods, utility fields, benefits and drawbacks, and prospects.

 

Islet, thyroid and transglutaminase antibodies in grownup Bulgarian sufferers with kind 1 diabetes

 

Goal: The goal of the examine was to evaluate the prevalence and relationship of islet antibodies and autoantibodies of the commonest related autoimmune diseases-autoimmune thyroid illness (AITD) and celiac illness, in grownup Bulgarian sufferers with kind 1 diabetes of brief period.
Materials and strategies: 160 kind 1 diabetes sufferers, of imply age 36.3 ± 10.9 years, imply BMI 23.0 ± 4.2 kg/m2 and imply illness period 1.35 ± 1.69 years have been enrolled. Pancreatic islet cell antibodies-glutamic acid decarboxylase antibodies (GAD 65-Ab), tyrosine phosphatase antibodies (IA 2-Ab), and zinc transporter Eight antibodies (ZnT8-Ab), thyroid antibodies-thyroperoxidase and thyroglobulin antibodies, and transglutaminase antibodies (TTG-IgA-Ab) have been assessed by ELISA.
Outcomes: 87.5% of the sufferers had a number of of the islet antibodies-78.1% had GAD 65-Ab, 53.1%-ZnT8-Ab, and 34.4%-IA 2-Ab. 5% introduced as simply ZnT8-Ab constructive. GAD 65-Ab recognized 90.6% of the antibody constructive sufferers. The addition of IA 2-Ab as a second immunologic marker recognized 94.4%, whereas the usage of ZnT8-Ab in second place recognized 98.8% of the instances. 24.4% introduced with constructive thyroid antibodies and 33.8% had AITD. No relation was discovered between any of the islet antibodies and AITD. Not one of the sufferers was TTG-IgA-Ab constructive. No vital correlations have been established between the antibodies with completely different organ specificity.
Conclusions: In grownup Bulgarian kind 1 diabetes sufferers ZnT8-Ab is an impartial diagnostic marker ranking second in prevalence and diagnostic significance after GAD 65-Ab. AITD impacts about one third of this inhabitants and routine screening is required, whereas screening for celiac illness shouldn’t be justified.
Key phrases: Autoimmune thyroid illness; Autoimmunity; Celiac illness; Islet antibodies; Sort 1 diabetes.

Eph Receptors as Most cancers Targets for Antibody-based Remedy

Receptor tyrosine kinases (RTKs) are integral membrane sensors that govern cell differentiation, proliferation and mobility, and allow fast communication between cells and their setting. Of the 20 RTK subfamilies at present identified, Eph receptors are the most important group.

Macranthoidin B

HY-N0864 10mg
EUR 589.2

Macranthoidin B

TB0339-1000 20mg
EUR 243.6

Macranthoidin A

TB0460-0020 25mg
EUR 298.8

Macrophage Marker (Macrophage L1 Protein) (Calprotectin); Clone MAC387 (Concentrate)

RA0287-C.1 0.1 ml
EUR 150

Macrophage Marker (Macrophage L1 Protein) (Calprotectin); Clone MAC387 (Concentrate)

RA0287-C.5 0.5 ml
EUR 360

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCA0035-250 250uL
EUR 459.6
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), APC conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC810035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF680R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC810035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF680R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC800035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF680 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC800035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF680 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC940035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF594 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC940035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF594 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC880035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF488A conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC880035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF488A conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC430035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF543 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC430035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF543 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC400035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF640R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC400035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF640R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC050035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF405M conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC050035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF405M conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCB0035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Biotin conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCB0035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Biotin conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCAP0035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCAP0035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCR0035-250 250uL
EUR 459.6
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), RPE conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNUB0035-100 100uL
EUR 250.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Concentration: 0.2mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNUB0035-500 500uL
EUR 549.6
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Concentration: 0.2mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCP0035-250 250uL
EUR 459.6
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), PerCP conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCH0035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNCH0035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNUM0035-50 50uL
EUR 474
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), 1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC040035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF405S conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC040035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF405S conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC550035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF555 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC550035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF555 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC610035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF660R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC610035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF660R conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC680035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF568 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC680035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF568 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC470035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF647 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC470035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF647 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC700035-100 100uL
EUR 238.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF770 conjugate, Concentration: 0.1mg/mL

Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387) Antibody

BNC700035-500 500uL
EUR 652.8
Description: Primary antibody against Calgranulin B / MRP-8/-14 / MAC 387 / S100A8/A9 / Macrophage Ag(MAC387), CF770 conjugate, Concentration: 0.1mg/mL

Monoclonal Macrophage L1 Protein Antibody - With BSA and Azide, Clone: MAC387

AMM01309G 0.05mg
EUR 475.2
Description: A Monoclonal antibody against Human Macrophage L1 Protein - With BSA and Azide. The antibodies are raised in Mouse and are from clone MAC387. This antibody is applicable in IHC, IF, FC

Monoclonal Macrophage L1 Protein Antibody - Without BSA and Azide, Clone: MAC387

AMM01310G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human Macrophage L1 Protein - Without BSA and Azide. The antibodies are raised in Mouse and are from clone MAC387. This antibody is applicable in IHC, IF, FC

Macrod1/ Rat Macrod1 ELISA Kit

ELI-31453r 96 Tests
EUR 1063.2

Cuvette Macro UV 2.5ml 5macro 2 Windows Disposable

CEL1018 PK100
EUR 73.2

Human macrocreatine kinase,macro-CK ELISA Kit

201-12-0835 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human macrocreatine kinase(macro-CK)ELISA Kit

GA-E0851HM-48T 48T
EUR 346.8

Human macrocreatine kinase(macro-CK)ELISA Kit

GA-E0851HM-96T 96T
EUR 559.2

Human macrocreatine kinase(macro-CK)ELISA Kit

QY-E02728 96T
EUR 433.2

Human macrocreatine kinase,macro-CK ELISA Kit

YLA2427HU-48T 48T
EUR 435

Human macrocreatine kinase,macro-CK ELISA Kit

YLA2427HU-96T 96T
EUR 562.5

MAC13243

HY-14456A 10mM/1mL
EUR 620.4

Mouse MACRO domain- containing protein 2, Macrod2 ELISA KIT

ELI-37419m 96 Tests
EUR 1038
  • Along with their corresponding ephrin ligands, Eph receptors regulate a various array of physiologic processes together with axonal steerage, bone transforming, and immune cell growth and trafficking.

 

  • Deregulation of Eph signaling pathways is linked to most cancers and different proliferative ailments and, as a result of RTKs play crucial roles in most cancers growth, the particular concentrating on of those molecules in malignancies offers a promising therapy strategy.

 

  • Monoclonal antibodies concentrating on RTKs symbolize a doubtlessly engaging modality for pharmaceutical growth attributable to their comparatively excessive goal specificity and low off-target binding charges.

 

Subsequently, new applied sciences to generate antibodies capable of goal RTKs of their native in vivo context are more likely to facilitate pre-clinical and medical growth of antibody-based therapies. Our group has lately reported a platform discovery methodology termed Choice of Phage-displayed Accessible Recombinant Focused Antibodies (SPARTA).

 

SPARTA is a novel and sturdy stepwise methodology, which mixes the attributes of in vitro screenings of a naïve human recombinant antibody library in opposition to identified tumor targets with these options of in vivo picks based mostly on tumor-homing capabilities of a pre-enriched antibody pool. This distinctive strategy overcomes a number of rate-limiting challenges to generate human monoclonal antibodies amenable to fast translation into medical purposes.