You are currently viewing HNS Antibody
HNS Antibody

HNS Antibody

 

 

Synonyms Anti-Human IgG Fc Monoclonal Secondary Antibody (Min X Ms, Rt, Rb, Ch, Gt)
Description Typically, goat anti-human or donkey anti-human IgG polyclonal antibodies are used because the secondary antibody to detect human major antibodies. Nevertheless, since polyclonal antibodies can acknowledge many epitopes, the background and the cross reactivity within the assays is normally excessive, making the outcomes onerous to interpret.
To attenuate the background and cross reactivity and enhance the lot-to-lot consistency, a novel GenScript Mouse Anti-Human IgG Fc Antibody (50B4A9)[HRP], mAb has been developed for use as a secondary antibody. The prevalence of this antibody is that it may be used as an idiotype antibody to detect drug metabolism in vivo.
Host Species Mouse
Antigen Species Human
Conjugation Peroxidase (Horseradish)
Immunogen Human IgG(H&L)
Purification Protein A affinity column

 

 

Working concentrations for particular purposes needs to be decided by the investigator. The suitable concentrations could also be affected by major antibody affinity, antigen focus, the sensitivity of the tactic of detection, temperature, the size of the incubations, and different elements. The suitability of this antibody for purposes apart from these listed under has not been decided. The next focus ranges are really helpful beginning factors for this product.

hns, Polyclonal Antibody
hns, Polyclonal Antibody

Anti-NHS antibodies are supplied by quite a few suppliers. This goal gene encodes the protein ‘NHS actin reworking regulator’ in people and may additionally be often called CTRCT40, CXN, SCML1, Nance-Horan syndrome protein, and Nance-Horan syndrome (congenital cataracts and dental anomalies). Structurally, the protein is reported to be 179.1 kilodaltons in mass. Primarily based on gene title, canine, porcine, monkey, mouse and rat orthologs may additionally be discovered. For extra complete antibody product data (comparable to immunogen, specificity, purposes, and extra), go to the provider web page.

Summary

Histone-like nucleoid structuring protein (H-NS) is a modular protein that’s related to the bacterial nucleoid. We used chromatin immunoprecipitation to find out the binding websites of H-NS and RNA polymerase on the Salmonella enterica serovar Typhimurium chromosome. We discovered that H-NS doesn’t bind to actively transcribed genes and doesn’t co-localize with RNA polymerase. This reveals that H-NS principally silences gene expression by limiting the entry of RNA polymerase to the DNA. H-NS had beforehand been proven to preferentially bind to curved DNA in vitro. The truth is, on the genomic degree we found that the extent of H-NS binding correlates higher with the AT-content of DNA. That is prone to have evolutionary penalties as a result of we present that H-NS binds to many Salmonella genes acquired by lateral gene switch, and capabilities as a gene silencer. The elimination of H-NS from the cell causes un-controlled expression of a number of Salmonella pathogenicity islands, and we reveal that this has deleterious penalties for bacterial health. Our discovery of this novel function for H-NS might have implications for the acquisition of overseas genes by enteric micro organism.

Synopsis

In latest many years, gene silencing has been well-characterised in vegetation and animals, and includes the prevention of transcription by DNA-methylation and histone-modification, or interference with translation by small RNA molecules. This problem of PLoS Pathogens studies the invention that world gene silencing additionally happens in micro organism. The novel mechanism is mediated by the extremely ample histone-like nucleoid structuring protein (H-NS), which blocks the expression of 254 genes in wild-type Salmonella. Many of those genes have been acquired by horizontal gene switch, together with pathogenicity islands, and these are silenced by the binding of H-NS to AT-rich chromosomal areas. The research reveals that H-NS prevents the uncontrolled transcription of genes inside pathogenicity islands to make sure that bacterial health is maintained. It’s urged that H-NS performs a task in bacterial evolution by influencing each the acquisition and upkeep of overseas DNA.

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML 0.4 ml
EUR 379

Antibody

A1360-500 Ask for price

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 469.2

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 577.2

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Leave a Reply