One of many main present tendencies in most cancers immunotherapy is the blockade of immune checkpoint proteins that negatively regulate the immune response. This has been achieved by antibodies blocking PD-1/PD-L1 and CTLA-4/CD80/CD86 interactions. Such antibodies have revolutionized oncological remedy and proven a brand new method to battle most cancers. Further (unfavourable) immune checkpoints are additionally promising targets in most cancers remedy and there’s a demand for inhibitors for these molecules. Our research are targeted on BTLA/HVEM advanced, which inhibits T-cell proliferation and cytokine manufacturing and subsequently has nice potential as a brand new goal for most cancers remedy. The purpose of the offered research was the design and synthesis of compounds in a position to block BTLA/HVEM interactions.
For that objective, the N-terminal fragment of glycoprotein D (gD), which interacts with HVEM, was used. Based mostly on the crystal construction of the gD/HVEM advanced and MM/GBSA evaluation carried out on it, a number of peptides had been designed and synthesized as potential inhibitors of the BTLA/HVEM interplay. Affinity checks, ELISA checks, and cellular-based reporter assays had been carried out on these compounds to verify their capacity to bind to HVEM and to inhibit BTLA/HVEM advanced formation. For main peptides candidates, all-atom and subsequent docking simulations with a coarse-grained pressure area had been carried out to find out their binding modes.
To additional consider their potential as drug candidates, their stability in plasma and their cytotoxicity results on PBMCs had been assessed. Our information point out that the peptide gD(1-36)(Okay10C-T29C) is the greatest candidate as a future drug. It interacts with HVEM protein, blocks the BTLA/HVEM interplay, and is unhazardous to cells. The current examine gives a brand new perspective on the event of BTLA/HVEM inhibitors that disrupt protein interactions.
Outcomes of an early security evaluation of a examine of the mixture of pembrolizumab and pelvic chemoradiation in regionally superior cervical most cancers
Background: Immune checkpoint inhibitors are being thought-about for regionally superior cervical most cancers (LACC) along with standard-of-care pelvic chemoradiation (CRT). Nevertheless, the protection of the mixture and its optimum schedule are unknown. Defining the protection of the mixture is a major goal of a examine inspecting concurrent and sequential schedules. This text presents a security evaluation that was totally accrued and met reporting necessities.
Strategies: Pembrolizumab was given after CRT (arm 1) or throughout CRT (arm 2) in keeping with a randomized part 2 design. Sufferers who had been 18 years previous or older and had LACC (levels IB-IVA in keeping with the 2009 Worldwide Federation of Gynecology and Obstetrics system) had been randomized 1:1 to the remedy regimens. The CRT was equivalent within the 2 arms. Pembrolizumab was administered each three weeks for three doses; no upkeep was allowed. All sufferers receiving any remedy had been evaluated for security. Security assessments included the incidence and severity of adversarial occasions (AEs) and the prevalence of protocol-defined dose-limiting toxicity (DLT) by 30 days after the final pembrolizumab infusion.
Outcomes: As of August 2019, 52 of the 88 deliberate sufferers had accomplished remedy and had been evaluable for toxicity. Remedy-related grade 2 or increased toxicity was skilled by 88%; 11 had at the least 1 grade Four AE, and one other 23 had at the least 1 grade three AE. Grade 1 or increased diarrhea was reported in 34 sufferers, and there was no distinction between arms. Two sufferers skilled three DLTs. Most sufferers accomplished cisplatin (100% in arm 1 vs 82% in arm 2); 83% in each arms accomplished all pembrolizumab.
Conclusions: Preliminary outcomes help the protection and feasibility of including pembrolizumab to pelvic CRT concurrently or sequentially.
Lay abstract: Pembrolizumab is a humanized antibody towards programmed cell demise protein 1 that’s utilized in most cancers immunotherapy. Preliminary information counsel that pembrolizumab may be safely mixed with chemotherapy and pelvic radiation within the remedy of regionally superior cervical most cancers. Future research of the addition of immunotherapy to conventional chemoradiation are deliberate to find out the greatest method to ship the remedy and whether or not any enchancment is seen with the addition of immunotherapy to conventional remedy.
Balancing the Affinity and Pharmacokinetics of Antibodies by Modulating the Dimension of Cost Patches on Complementarity-Figuring out Areas
A localized optimistic cost on IgG (known as a “cost patch”) exhibits an adversarial impact on pharmacokinetics (PK), so it will appear to be greatest follow to keep away from cost patches through the discovery stage and intently monitor cost interactions through the growth course of. In sure circumstances, nevertheless, cost patches are required for goal binding, through which case fully eradicating cost patches just isn’t possible.
Due to this fact, quantitative measurement of a cost patch and its impression on PK is important to the success of therapeutic antibody growth. On this article, we generated mutations of a recombinant human antibody (known as mAb1) with disrupted cost patches to research how cost patches on IgG antibodies impression each target-binding affinity and PK-related elements. We conclude that you will need to modulate the dimensions of the cost patch to be able to steadiness target-binding affinity and PK.
HO-1 ELISA Kit |
SKT-111-96 |
Stressmarq |
1 plate of 96 wells |
EUR 702 |
|
Description: Sandwich ELISA kit used for quantitate HO-1 concentration in Cell Lysates, Tissue, Serum, Cyst fluid samples from Human, Rat |
HO-1 ELISA Kit| Rat Heme Oxygenase 1 ELISA Kit |
EF017799 |
Lifescience Market |
96 Tests |
EUR 826.8 |
HO-1 ELISA Kit| Mouse Heme Oxygenase 1 ELISA Kit |
EF013687 |
Lifescience Market |
96 Tests |
EUR 826.8 |
ELISA kit for Human HO-1/HMOX1 |
EK5397 |
SAB |
96 tests |
EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human HO-1/HMOX1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Rat heme oxygenase 1,HO-1 ELISA Kit |
CN-01878R1 |
ChemNorm |
96T |
EUR 548.4 |
Rat heme oxygenase 1,HO-1 ELISA Kit |
CN-01878R2 |
ChemNorm |
48T |
EUR 367.2 |
Rat heme oxygenase 1, HO-1 ELISA Kit |
CSB-E08267r-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Rat heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Rat heme oxygenase 1, HO-1 ELISA Kit |
1-CSB-E08267r |
Cusabio |
-
EUR 1160.40
-
EUR 7110.00
-
EUR 3760.80
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Rat heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Rat HO-1(Heme Oxygenase 1) ELISA Kit |
ER1041 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml |
Rat heme oxygenase 1(HO-1)ELISA Kit |
GA-E0684RT-48T |
GenAsia Biotech |
48T |
EUR 380.4 |
Rat heme oxygenase 1(HO-1)ELISA Kit |
GA-E0684RT-96T |
GenAsia Biotech |
96T |
EUR 595.2 |
Human heme oxygenase 1,HO-1 ELISA Kit |
201-12-0933 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Mouse heme oxygenase 1,HO-1 ELISA Kit |
CN-02756M1 |
ChemNorm |
96T |
EUR 548.4 |
Mouse heme oxygenase 1,HO-1 ELISA Kit |
CN-02756M2 |
ChemNorm |
48T |
EUR 367.2 |
Human heme oxygenase 1,HO-1 ELISA Kit |
CN-04663H1 |
ChemNorm |
96T |
EUR 556.8 |
Human heme oxygenase 1,HO-1 ELISA Kit |
CN-04663H2 |
ChemNorm |
48T |
EUR 375.6 |
Human heme oxygenase 1, HO-1 ELISA Kit |
CSB-E08266h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human heme oxygenase 1, HO-1 ELISA Kit |
1-CSB-E08266h |
Cusabio |
-
EUR 1080.00
-
EUR 6571.20
-
EUR 3480.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse heme oxygenase 1, HO-1 ELISA Kit |
CSB-E08268m-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Mouse heme oxygenase 1, HO-1 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse heme oxygenase 1, HO-1 ELISA Kit |
1-CSB-E08268m |
Cusabio |
-
EUR 1135.20
-
EUR 6938.40
-
EUR 3672.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Mouse heme oxygenase 1, HO-1 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human heme oxygenase 1(HO-1)ELISA Kit |
GA-E0949HM-48T |
GenAsia Biotech |
48T |
EUR 346.8 |
Human heme oxygenase 1(HO-1)ELISA Kit |
GA-E0949HM-96T |
GenAsia Biotech |
96T |
EUR 559.2 |
Mouse heme oxygenase 1(HO-1)ELISA Kit |
GA-E0279MS-48T |
GenAsia Biotech |
48T |
EUR 403.2 |
Mouse heme oxygenase 1(HO-1)ELISA Kit |
GA-E0279MS-96T |
GenAsia Biotech |
96T |
EUR 640.8 |
Mouse HO-1(Heme Oxygenase 1) ELISA Kit |
EM1128 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
Human HO-1/HMOX1 PicoKine ELISA Kit |
EK0888 |
BosterBio |
96 wells |
EUR 510 |
Description: For quantitative detection of human HO-1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Sheep Heparin-binding growth factor 1(HO-1)ELISA Kit |
YLA0056SH-48T |
Shanghai YL Biotech |
48T |
EUR 540 |
Sheep Heparin-binding growth factor 1(HO-1)ELISA Kit |
YLA0056SH-96T |
Shanghai YL Biotech |
96T |
EUR 645 |
HO-2 ELISA Kit| Rat heme oxygenase 2 ELISA Kit |
EF017800 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Brms1 ELISA Kit| Mouse Breast cancer metastasis-suppressor 1 ho |
EF014335 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Rat heme oxygenase 2,HO-2 ELISA Kit |
CN-01837R1 |
ChemNorm |
96T |
EUR 556.8 |
Rat heme oxygenase 2,HO-3 ELISA Kit |
CN-01837R2 |
ChemNorm |
48T |
EUR 375.6 |
Rat HO-2(heme oxygenase 2) ELISA Kit |
ER1042 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.938mU/ml |
Rat heme oxygenase 2(HO-2)ELISA Kit |
GA-E0685RT-48T |
GenAsia Biotech |
48T |
EUR 380.4 |
Rat heme oxygenase 2(HO-2)ELISA Kit |
GA-E0685RT-96T |
GenAsia Biotech |
96T |
EUR 595.2 |
Human heme oxygenase 2,HO-2 ELISA Kit |
201-12-0894 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Mouse heme oxygenase 2,HO-2 ELISA Kit |
CN-02714M1 |
ChemNorm |
96T |
EUR 549.6 |
Mouse heme oxygenase 2,HO-2 ELISA Kit |
CN-02714M2 |
ChemNorm |
48T |
EUR 368.4 |
Human heme oxygenase 2,HO-2 ELISA Kit |
CN-04658H1 |
ChemNorm |
96T |
EUR 529.2 |
Human heme oxygenase 2,HO-2 ELISA Kit |
CN-04658H2 |
ChemNorm |
48T |
EUR 349.2 |
Human heme oxygenase 2, HO-2 ELISA Kit |
CSB-E08408h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 2, HO-2 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human heme oxygenase 2, HO-2 ELISA Kit |
1-CSB-E08408h |
Cusabio |
-
EUR 1080.00
-
EUR 6571.20
-
EUR 3480.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 2, HO-2 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human heme oxygenase 2(HO-2)ELISA Kit |
GA-E0910HM-48T |
GenAsia Biotech |
48T |
EUR 346.8 |
Human heme oxygenase 2(HO-2)ELISA Kit |
GA-E0910HM-96T |
GenAsia Biotech |
96T |
EUR 559.2 |
Mouse heme oxygenase 2(HO-2)ELISA Kit |
GA-E0394MS-48T |
GenAsia Biotech |
48T |
EUR 403.2 |
Mouse heme oxygenase 2(HO-2)ELISA Kit |
GA-E0394MS-96T |
GenAsia Biotech |
96T |
EUR 640.8 |
HO-2 ELISA Kit| Mouse Heme Oxygenase 2, Decycling ELISA Kit |
EF013688 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Mouse HO-2(Heme Oxygenase 2, Decycling) ELISA Kit |
EM1129 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.375 ng/ml |
Anti-HO-1 Monoclonal Antibody (HO-1-2) |
M00253-1 |
BosterBio |
1mg |
EUR 476.4 |
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
HO-1 protein |
E20-80037 |
EnoGene |
20ug |
EUR 489.6 |
HO-1 Antibody |
R31625 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Heme oxygenase (decycling) 1, also known as HO-1, is an essential enzyme in heme catabolism. HO-1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HO-1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HO-1 activity is induced by its substrate heme and by various nonheme substances. |
Smad1/MADH1 ELISA Kit| Rabbit Mothers Against Decapentaplegic Ho |
EF016874 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Rtf1 ELISA Kit| Mouse RNA polymerase-associated protein RTF1 ho |
EF016125 |
Lifescience Market |
96 Tests |
EUR 826.8 |
Rat Heme Oxygenase 1 (HO-1) CLIA Kit |
abx195766-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Mouse Heme Oxygenase 1 (HO-1) CLIA Kit |
abx195765-96tests |
Abbexa |
96 tests |
EUR 990 |
|
HO-1 Polyclonal Antibody |
27513-100ul |
SAB |
100ul |
EUR 302.4 |
HO-1 Polyclonal Antibody |
27513-50ul |
SAB |
50ul |
EUR 224.4 |
HO-1 Polyclonal Antibody |
27573-100ul |
SAB |
100ul |
EUR 302.4 |
HO-1 Polyclonal Antibody |
27573-50ul |
SAB |
50ul |
EUR 224.4 |
HO-1 Rabbit pAb |
A11102-100ul |
Abclonal |
100 ul |
EUR 369.6 |
HO-1 Rabbit pAb |
A11102-200ul |
Abclonal |
200 ul |
EUR 550.8 |
HO-1 Rabbit pAb |
A11102-20ul |
Abclonal |
20 ul |
EUR 219.6 |
HO-1 Rabbit pAb |
A11102-50ul |
Abclonal |
50 ul |
EUR 267.6 |
HO-1 Rabbit pAb |
A11919-100ul |
Abclonal |
100 ul |
EUR 460.8 |
HO-1 Rabbit pAb |
A11919-200ul |
Abclonal |
200 ul |
Ask for price |
HO-1 Rabbit pAb |
A11919-20ul |
Abclonal |
20 ul |
Ask for price |
HO-1 Rabbit pAb |
A11919-50ul |
Abclonal |
50 ul |
EUR 318 |
HO-1 Rabbit pAb |
A1346-100ul |
Abclonal |
100 ul |
EUR 369.6 |
HO-1 Rabbit pAb |
A1346-200ul |
Abclonal |
200 ul |
EUR 550.8 |
HO-1 Rabbit pAb |
A1346-20ul |
Abclonal |
20 ul |
EUR 219.6 |
HO-1 Rabbit pAb |
A1346-50ul |
Abclonal |
50 ul |
EUR 267.6 |
HO-1 Blocking Peptide |
AF5393-BP |
Affbiotech |
1mg |
EUR 234 |
HO-1 Recombinant Protein |
91-128 |
ProSci |
0.05 mg |
EUR 651.3 |
Description: Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues. |
Rat HO-1 Protein |
SPR-315A |
Stressmarq |
0.05 mg |
EUR 313.2 |
|
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested. |
Rat HO-1 Protein |
SPR-315B |
Stressmarq |
0.1 mg |
EUR 501.6 |
|
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested. |
Rat HO-1 Protein |
SPR-315C |
Stressmarq |
2x0.1 mg |
EUR 676.8 |
|
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested. |
Human Heme Oxygenase (HO/HMOX1/HSP32) ELISA Kit, 96 tests, Quantitative |
100-540-HO1 |
Alpha Diagnostics |
1 Kit |
EUR 854.4 |
HO-3867 |
B4970-25 |
ApexBio |
25 mg |
EUR 640.8 |
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis. |
HO-3867 |
B4970-5 |
ApexBio |
5 mg |
EUR 254.4 |
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis. |
HO-3867 |
B4970-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 351.6 |
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis. |
Heme Oxygenase 1 (HO-1) Antibody |
20-abx444865 |
Abbexa |
|
|
|
Heme Oxygenase 1 (HO-1) Antibody |
abx444939-100ug |
Abbexa |
100 ug |
EUR 627.6 |
|
Heme Oxygenase 1 (HO-1) Antibody |
20-abx445136 |
Abbexa |
|
|
|
Heme Oxygenase 1 (HO-1) Antibody |
abx448465-100ug |
Abbexa |
100 ug |
EUR 627.6 |
|
Heme Oxygenase 1(HO-1) Antibody |
48715-100ul |
SAB |
100ul |
EUR 399.6 |
Heme Oxygenase 1(HO-1) Antibody |
48715-50ul |
SAB |
50ul |
EUR 286.8 |
Heme Oxygenase 1 Antibody (HO-1) |
R36412-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: Heme oxygenase 1, HMOX1 |
Polyclonal HMOX1 / HO-1 Antibody |
APR07773G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications: |
Polyclonal HMOX1 / HO-1 Antibody |
APR07774G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications: |
Polyclonal HMOX1 / HO-1 Antibody |
APR07775G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications: |
HO-1 Mouse Monoclonal Antibody |
BF8020 |
Affbiotech |
100ul |
EUR 420 |
HO-1 Polyclonal Conjugated Antibody |
C27513 |
SAB |
100ul |
EUR 476.4 |
HO-1 Polyclonal Conjugated Antibody |
C27573 |
SAB |
100ul |
EUR 476.4 |
Anti-HO-1 Monoclonal Antibody |
M00253-2 |
BosterBio |
100ug |
EUR 476.4 |
Description: Mouse Monoclonal HO-1 Antibody. Validated in ELISA, IP, IF, IHC, WB and tested in Human, Mouse, Rat. |
Monoclonal antibody for HO-1 |
SMC-131C |
Stressmarq |
0.025mg |
EUR 248.4 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is not conjugated. |
Monoclonal antibody for HO-1 |
SMC-131D |
Stressmarq |
0.1mg |
EUR 428.4 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is not conjugated. |
Monoclonal antibody for HO-1 |
SMC-131D-A390 |
Stressmarq |
0.1mg |
EUR 484.8 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 390. |
Monoclonal antibody for HO-1 |
SMC-131D-A488 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 488. |
Monoclonal antibody for HO-1 |
SMC-131D-A565 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 565. |
Monoclonal antibody for HO-1 |
SMC-131D-A594 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 594. |
Monoclonal antibody for HO-1 |
SMC-131D-A633 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 633. |
Monoclonal antibody for HO-1 |
SMC-131D-A655 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 655. |
Monoclonal antibody for HO-1 |
SMC-131D-A680 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 680. |
Monoclonal antibody for HO-1 |
SMC-131D-A700 |
Stressmarq |
0.1mg |
EUR 483.6 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with ATTO 700. |
Monoclonal antibody for HO-1 |
SMC-131D-ALP |
Stressmarq |
0.1mg |
EUR 476.4 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with Alkaline Phosphatase. |
Monoclonal antibody for HO-1 |
SMC-131D-APC |
Stressmarq |
0.1mg |
EUR 482.4 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with APC. |
Monoclonal antibody for HO-1 |
SMC-131D-APCCY7 |
Stressmarq |
0.1mg |
EUR 568.8 |
|
Description: A monoclonal antibody from clone 1F12-A6 against Human | Mouse | Rat | Bovine | Chicken HO-1. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human HO-1 synthetic peptide, amino acids 1-30. The antibody is tested and validated for WB, IHC, ICC/IF, IP, ELISA assays with the following recommended dilutions: WB (1:1000), IHC (1:100), ICC/IF (1:100). This MAb for HO-1 is conjugated with APC/Cy7. |
Avelumab, an antiprogrammed demise ligand-1 antibody, is authorized as a monotherapy for remedy of metastatic Merkel cell carcinoma and superior urothelial carcinoma, and together with axitinib for superior renal cell carcinoma. We report the efficacy and security of first-line avelumab in superior non-small cell lung most cancers (NSCLC).